反应详情

温度

50 °C

A mixture of N-(3-amino-4-fluorobenzyl)-1-(trifluoromethyl)cyclopropanecarboxamide (3.17 g; 11.5 mmol) and TCDI (3.07 g; 17.2 mmol) in DCM (50 mL) was heated overnight at 50° C. The mixture was concentrated and the residue was purified by column chromatography.

1. concentrationThe mixture was concentrated
2. customthe residue was purified by column chromatography