Nitric Acid → HCID 59529860, compound

HRID 1258736Notes

Reaction equation

HRID 1258736 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([F:10])[CH:3]=1.[N+:11]([O-])([OH:13])=[O:12]>OS(O)(=O)=O>[Cl:1][C:2]1[C:9]([N+:11]([O-:13])=[O:12])=[CH:8][C:5]([C:6]#[N:7])=[C:4]([F:10])[CH:3]=1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 936554-Chloro-2-fluorobenzonitrile

Product 1

HCID 59529860HCID 59529860, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Conditions

Temperature
1.5 °C

Procedure

A mixture of 4-chloro-2-fluorobenzonitrile (4.62 g; 29.7 mmol) in conc. H2SO4 (42 mL) was treated dropwise with conc. HNO3 (3.9 mL) at 1-2° C. After stirring at 1-2° C. for 2 h the mixture was poured into ice and filtered.

Workup

  1. additionwas poured into ice
  2. filtrationfiltered

Sources & evidence

ORD record
ord-91c83f608c054a85b54e844fde84b877
Source dataset
uspto-grants-2013_06
Patent number
US08466186B2

Reaction notes

Loading…