3-Amino-3-(3,4-dimethoxyphenyl)propanoic acid → Methyl 3-amino-3-(4-ethoxy-3-methoxyphenyl)propanoate

HRID 1258791Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1258791
N[CH:2](C1C=CC(OC)=C(OC)C=1)CC(O)=O.[NH2:17][CH:18]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][CH3:31])=[C:25]([O:32][CH3:33])[CH:24]=1)[CH2:19][C:20]([OH:22])=[O:21]>>[NH2:17][CH:18]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][CH3:31])=[C:25]([O:32][CH3:33])[CH:24]=1)[CH2:19][C:20]([O:22][CH3:2])=[O:21]

Komponenten

3

Edukt 2

HCID 5971823-Amino-3-(3,4-dimethoxyphenyl)propanoic acidHCID 6020003-Amino-3-(4-ethoxy-3-methoxyphenyl)propanoic acid

Produkt 1

HCID 5121114Methyl 3-amino-3-(4-ethoxy-3-methoxyphenyl)propanoate

Versuchsvorschrift

The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)propionic acid was substituted with 3-amino-3-(3-methoxy-4-ethoxy-phenyl)propionic acid. 1H NMR (CDCl3): δ 6.79-6.90 (m, 3H), 4.37 (q, 1H, J=5 Hz), 4.06 (q, 2H, J=5 Hz), 3.86 (s, 3H), 3.67 (s, 3H), 2.63 (d, 2H, J=5 Hz), 1.80 (s, 2H), 1.43 (t, 3H, J=5 Hz).

Quellen und Nachweise

ORD-Eintrag
ord-86f326a69ed748cd8b2ab22b20476396
Quelldatensatz
uspto-grants-2013_06
Patentnummer
US08466191B2

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