3-Amino-3-[4-(benzyloxy)phenyl]propanoic acid → Methyl 3-Amino-3-[4-(phenylmethoxy)phenyl]propionate
Reaction equation
N[CH:2](C1C=CC(OC)=C(OC)C=1)CC(O)=O.[NH2:17][CH:18]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)=[CH:25][CH:24]=1)[CH2:19][C:20]([OH:22])=[O:21]>>[NH2:17][CH:18]([C:23]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)=[CH:25][CH:24]=1)[CH2:19][C:20]([O:22][CH3:2])=[O:21]Participants
3
Procedure
The title compound was prepared following the method for preparing Intermediate 6 except that 3-amino-3-(3,4-dimethoxy-phenyl)propionic acid was substituted with 3-amino-3-(4-benzyloxy phenyl)propionic acid.
Sources & evidence
- ORD record
- ord-51cea10f6a5842bbb4860baa0be21b2c
- Source dataset
- uspto-grants-2013_06
- Patent number
- US08466191B2
Reaction notes
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