3-Amino-3-(4-ethoxy-3-methoxyphenyl)propanoic acid → Ethyl 3-amino-3-(4-ethoxy-3-methoxyphenyl)propanoate

HRID 1258801Notes

Reaction equation

HRID 1258801 reaction equation
N[CH:2](C1C=CC(OC)=C(OCC)C=1)[CH2:3]C(O)=O.[NH2:18][CH:19]([C:24]1[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH3:32])=[C:26]([O:33][CH3:34])[CH:25]=1)[CH2:20][C:21]([OH:23])=[O:22]>>[NH2:18][CH:19]([C:24]1[CH:29]=[CH:28][C:27]([O:30][CH2:31][CH3:32])=[C:26]([O:33][CH3:34])[CH:25]=1)[CH2:20][C:21]([O:23][CH2:2][CH3:3])=[O:22]

Participants

3

Reactant 2

HCID 6020003-Amino-3-(4-ethoxy-3-methoxyphenyl)propanoic acidHCID 41021513-Amino-3-(3-ethoxy-4-methoxyphenyl)propanoic acid

Product 1

HCID 4201977Ethyl 3-amino-3-(4-ethoxy-3-methoxyphenyl)propanoate

Procedure

The title compound was prepared following the method for preparing Intermediate 26 except that 3-amino-3-(3-ethoxy-4-methoxy-phenyl)propionic acid was substituted with 3-amino-3-(3-methoxy-4-ethoxy-phenyl)propionic acid. MS (m/z): 268 [M+1]+.

Sources & evidence

ORD record
ord-45236eafa5df4fa3bd3187809103738a
Source dataset
uspto-grants-2013_06
Patent number
US08466191B2

Reaction notes

Loading…