4-Aminotetrahydropyran → HCID 57378670, compound

Participants

Reaction Steps

As described for example 3b, 4-{4-[5-(4-fluoro-phenyl)-3-methyl-3H-[1,2,3]triazol-4-yl]-imidazol-1-yl}-benzoic acid (75 mg, 0.21 mmol) was converted, using 4-aminotetrahydropyran instead of isopropylamine, to the title compound (73 mg, 79%) which was obtained as a white solid. MS: m/e=447.3 [M+H]+.

Provenance & Evidence