N-Aminomorpholine → HCID 57377363, compound

Participants

Reaction Steps

As described for example 22, 6-(4-(4-(2-fluorophenyl)-1-methyl-1H-1,2,3-triazol-5-yl)-1H-imidazol-1-yl)nicotinic acid (69 mg, 0.189 mmol) was converted, using 4-aminomorpholine instead of 4-aminotetrahydropyran, to the title compound (59 mg, 70%) which was obtained as a white foam after purification by chromatography (silica, 0 to 10% methanol in dichloromethane). MS: m/e=449.2 [M+H]+.

Provenance & Evidence