Allyl bromide → 2-Allyloxy-m-anisic acid

Participants

Reaction Steps

The reaction of methyl 2-hydroxy-3-methoxy-benzoate and allyl bromide in 2-butanone in the presence of potassium carbonate was performed as described in Example 2 to give 2-Allyloxy-3-methoxy-benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 12.18 (s, —CO2H); 7.10 (m, 3 arom. H); 5.97 (m, —CH═CH2); 5.28, 5.14 (2 d-like, CH═CH2); 4.43 (d-like, CH2—CH═CH2); 3.77 (s, OCH3). 13C-NMR (100 MHz, d6-DMSO): 167.42 (C═O); 153.06; 146.24; 134.49; 127.66; 123.94; 121.07; 117.10; 115.57; 73.88; 55.93.

Provenance & Evidence