HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 2-Allyloxy-5-chloro-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzoic acid, 5-chloro-2-hydroxy-, methyl ester | HCID 77684 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 2-Allyloxy-5-chloro-benzoic acid | HCID 1843886 | — |
Reaction Steps
The reaction of methyl 5-chloro-2-hydroxyl-benzoate and allyl bromide in 2-butanone in the presence of potassium carbonate was performed as described in Example 2 to give 2-Allyloxy-5-chloro-benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 12.96 (s, —CO2H); 7.61 (m, 1 arom. H); 7.52 (m, 1 arom. H); 7.12 (m, 1 arom. H); 5.99 (m, —CH═CH2); 5.47, 5.23 (2 d-like, CH═CH2); 4.62 (d-like, CH2—CH═CH2). 13C-NMR (100 MHz, d6-DMSO): 166.08 (C═O); 155.70; 133.02; 132.25; 129.84; 123.85; 123.36; 117.15; 115.70; 68.91.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466199B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-df972db762ea4eefbf5aff5cfa8586dd |
| Source note | uspto-grants-2013_06 |