HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromopropane → 2-Propoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromopropane | HCID 7840 | — |
| Reactant | Ethyl Salicylate | HCID 8365 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-propoxybenzoic acid | HCID 586799 | — |
| Product | 2-Propoxybenzoic acid | HCID 539215 | — |
Reaction Steps
The reaction of propyl bromide and ethyl salicylate in the presence of potassium carbonate was performed as described for Compound 24 to give 2-Propoxy-benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 12.56 (s, COOH); 7.61 (m, 1 arom. H); 7.45 (m, 1 arom. H); 7.07 (m, 1 arom. H); 6.96 (m, 1 arom. H); 3.96 (t, CH3CH2CH2O); 1.71 (m, CH3CH2CH2O); 0.96 (t, CH3CH2CH2O). 13C-NMR (100 MHz, d6-DMSO): 167.49 (—C═O); 157.41; 132.82; 130.51; 121.73; 119.91; 113.35; 69.63; 22.04; 10.39.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466199B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-b7a178d97d824b05b589a7da97b18f98 |
| Source note | uspto-grants-2013_06 |