Sodium hydride → HCID 25056516, compound

Participants

Reaction Steps

The reaction of But-3-en-1-ol and 3-chloromethyl-benzoic acid in the presence of sodium hydride was performed as described for Compound 37 to give 3-But-3-enyloxymethyl-benzoic acid as colorless oil. 1H-NMR (400 MHz, d6-DMSO): 7.89 (m, 1 arom.H); 7.84 (m, 1 arom.H); 7.54 (m, 1 arom.H); 7.47 (m, 1 arom.H); 5.80 (m, —CH═CH2); 5.06 (2 d-like, —CH═CH2); 4.61 (s, —OCH2—C6H4); 3.49 (m, CH2—CH—CH2CH2O); 2.31 (m, CH2═CH—CH2CH2O). 13C-NMR (100 MHz, d6-DMSO): 167.14 (—C═O); 139.11; 135.52; 131.72; 130.76; 128.54; 128.27; 128.10; 126.44; 71.17; 69.06; 33.70.

Provenance & Evidence