HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)benzoic acid → HCID 2608779, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)benzoic acid | HCID 22599 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-But-3-enyloxymethyl-benzoic acid | HCID 22136996 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 2608779 | HCID 2608779 | — |
Reaction Steps
The reaction of isopropanol and 4-Bromomethyl-benzoic acid in the presence of sodium hydride was performed as described for Compound 33 to give 4-Isopropoxymethyl-benzoic acid as white powder. 1H-NMR (400 MHz, d6-DMSO): 7.89 (d, J=8.2, 2 arom.H); 7.41 (d, J=8.2, 2 arom.H); 4.51 (s, OCH2C6H4—); 3.63 (m, CH(CH3)2); 1.14 (d, CH(CH3)2). 13C-NMR (100 MHz, d6-DMSO): 167.24 (—C═O); 144.47; 129.52; 129.23 (2 arom.C); 126.93 (2 arom. C); 70.67; 68.47; 22.00 (2 C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466199B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-f4a4cc8f9f284d6882ed4ca35aaf7c5c |
| Source note | uspto-grants-2013_06 |