HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 68915115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Aminoadamantane hydrochloride | HCID 25331 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68915115 | HCID 68915115 | 94% |
Reaction Steps
A solution of 2-adamantylamine hydrochloride 3 g (15.98 mmol), carbonyldiimidazole 2.59 g (15.98 mmol), triethylamine 2.215 ml (15.98 mmol) in CH2Cl2 100 ml was stirred overnight at room temperature. Water was added, the organic phase separated, dried and concentrated to dryness yielding the title crude product 3.69 g (94%) as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466200B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-8e1abb79f81a4befbc59020d604598d8 |
| Source note | uspto-grants-2013_06 |