HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 23582289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 23582290 | HCID 23582290 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23582289 | HCID 23582289 | — |
Reaction Steps
A solution of 4-[2-(3-Adamantan-2-yl-1-methyl-ureido)-ethoxy]-benzoic acid methyl ester 562 mg (1.45 mmol), NaOH 1N 3 ml in THF 5 ml was stirred at RT overnight. Then NaOH 1N 4 ml was added and the reaction mixture stirred overnight. Water was added and the mixture acidified until pH=2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466200B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-716449167f384d67aa636d4e3af1e4d5 |
| Source note | uspto-grants-2013_06 |