Acetaldehyde → HCID 66875103, compound

HRID 1259134Notes

Reaction equation

[Br:1][C:2]1[C:3]([C:9]#[N:10])=[N:4][CH:5]=[C:6]([CH3:8])[CH:7]=1.[CH:11](=[O:13])[CH3:12]>>[Br:1][C:2]1[C:3]([C:9]#[N:10])=[N:4][CH:5]=[C:6]([CH2:8][CH:11]([OH:13])[CH3:12])[CH:7]=1

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 225912183-Bromo-5-methylpyridine-2-carbonitrile

Product 1

HCID 66875103HCID 66875103, compound

Procedure

3-Bromo-5-(2-hydroxypropyl)picolinonitrile was prepared from 3-bromo-5-methylpicolinonitrile (from the previous step) and acetaldehyde following the procedures described for Example 53/Step 3.

Sources & evidence

ORD record: ord-13b2945f173e44fba2029770f67108c8
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08466167B2

Reaction notes

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