Pyridine → 4-[3-(3-methoxypropyl)piperazin-1-yl]-2-propan-2-yl-10H-[1,3]thiazolo[5,4-b][1,5]benzodiazepine
Reaction equation
[CH3:28][O:29][CH2:30][CH2:31][CH2:32][CH:33]1[NH:34][CH2:35][CH2:36][NH:37][CH2:38]1.[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]2[c:12]([s:13]1)[NH:11][c:10]1[c:9]([cH:17][cH:16][cH:15][cH:14]1)[NH:8][C:7]2=[S:18].[Cl:45][CH2:46][Cl:47].[S:19]([O:20][CH3:21])([C:22]([F:23])([F:24])[F:25])(=[O:26])=[O:27].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]2[c:12]([s:13]1)[NH:11][c:10]1[c:9]([cH:17][cH:16][cH:15][cH:14]1)[N:8]=[C:7]2[N:37]1[CH2:36][CH2:35][NH:34][CH:33]([CH2:32][CH2:31][CH2:30][O:29][CH3:28])[CH2:38]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9f913094a1db4112ae836b08978dd08f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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