HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium thiocyanate → Potassium 3-(1,3-bis(benzyloxy)propan-2-yl)cyclobutane-1-sulfonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | Butyl 3-(1,3-bis(benzyloxy)propan-2-yl)cyclobutane-1-sulfonate | HCID 58380533 | — |
| Solvent | Water 1,2-dimethoxyethane | HCID 18180031 | — |
| Product | Potassium 3-(1,3-bis(benzyloxy)propan-2-yl)cyclobutane-1-sulfonate | HCID 86656334 | 83% |
Reaction Steps
Using the same reaction conditions, procedure and work up as described Intermediate I-25b (below), butyl 3-(1,3-bis(benzyloxy)propan-2-yl)cyclobutane-1-sulfonate (0.1 g, 0.22 mmol) was reacted with KSCN (24 mg, 0.24 mmol) and DME-water mixture (2 mL) to afford 0.07 g of the product (83% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466289B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-81750af68b554bc08113063ccc12c92a |
| Source note | uspto-grants-2013_06 |