HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 1-(diphenylmethyl)-5-methyl-1H-indole-2,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | 5-Methylisatin | HCID 11840 | — |
| Reactant | Bromodiphenylmethane | HCID 236603 | — |
| Reactant | (2-Bromoethyl)cyclopropane | HCID 22636989 | — |
| Product | 1-(diphenylmethyl)-5-methyl-1H-indole-2,3-dione | HCID 66642678 | — |
Reaction Steps
Following the procedure as described in PREPARATION 2A, and making non-critical variations to replace isatin with 5-methylisatin, and (2-bromoethyl)cyclopropane with 1,1′-(bromomethylene)dibenzene, the title compound was obtained (74%) as a bright orange solid: 1H NMR (300 MHz, CDCl3) δ 7.42-7.26 (m, 11H), 7.09 (d, 1H), 6.95 (s, 1H), 6.37 (d, 1H), 2.24 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08466188B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-8665f4163c774243b3bea929ccdda7fc |
| Source note | uspto-grants-2013_06 |