HCID 86655538, compound → HCID 67204737, compound

HRID 1259856Notes

Reaction equation

HRID 1259856 reaction equation
[C:1]1([C:7]2[CH:16]=[C:15]([C:17]([NH:19][C:20](=S)[NH:21][NH:22][C:23]([CH:25]3[CH2:29][CH2:28][CH2:27][O:26]3)=[O:24])=[O:18])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C2C=C(C(NC(=S)NNC(C3SC=CC=3)=O)=O)C3C(=CC=C(OC(F)(F)F)C=3)N=2)C=CC=CC=1>>[O:26]1[CH2:27][CH2:28][CH2:29][CH:25]1[C:23]1[O:24][C:20]([NH:19][C:17]([C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[N:8]=[C:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[CH:16]=2)=[O:18])=[N:21][N:22]=1

Participants

3

Reactant 2

HCID 86655538HCID 86655538, compoundHCID 86655539HCID 86655539, compound

Product 1

HCID 67204737HCID 67204737, compound

Procedure

The title compound was synthesized according to the synthesis method of the compound Ia-122 using 4-(2-phenyl-4-quinolinecarbonyl)-1-(2-tetrahydrofurancarbonyl)thiosemicarbazide described in Reference Example 38 instead of 4-(2-phenyl-6-trifluoromethoxy-4-quinolinecarbonyl)-1-(2-thiophenecarbonyl)thiosemicarbazide.

Workup

  1. customaccording to the synthesis method of the compound Ia-122

Sources & evidence

ORD record
ord-7b25b991ad914fb18e9814c6347b4a4c
Source dataset
uspto-grants-2013_06
Patent number
US08466290B2

Reaction notes

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