反应详情

The ethyl 2-(3,7-dimethylocta-2,6-dienylamino)-2-oxoacetate (1.5 g, 5.92 mmol) was mixed with 2-(pyridin-2-yl)ethanamine (1 g, 8.19 mmol) in ethanol (20 ml) to give a yellow solution. The reaction mixture was stirred at reflux for 1.5 hour. Then the solvent was removed by evaporation. The remaining residual solid was washed with ethanol/pentane to provide the target compound as white crystals (1.3 g; 65% yield). The product is ca. 97% pure according to NMR analysis.

1. customto give a yellow solution
2. temperatureat reflux for 1.5 hour
3. customThen the solvent was removed by evaporation
4. washThe remaining residual solid was washed with ethanol/pentane