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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260147Generated: October 25, 2026

Methyl L-prolinate → (S)-1-(2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonyl)-pyrrolidine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/1260147

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl L-prolinateHCID 853477—
Reactant2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonic acid propylamideHCID 11277178—
Product(S)-1-(2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonyl)-pyrrolidine-2-carboxylic acid methyl esterHCID 9840785—

Reaction Steps

The title compound was prepared from L-Pro-OMe following the procedure for 2,3-Dioxo-2,3-dihydro-1H-indole-5-sulfonic acid propylamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470782B2
Source datasetuspto-grants-2013_06
ORD IDord-1bda085f072a42e6a6238096f3daa84c
Source noteuspto-grants-2013_06