Indomethacin → KMUP-1 Indomethacin

Participants

Reaction Steps

KMUP-1 (8.0 g) is dissolved in a mixture of ethanol (100 mL) and water (30 mL), to which indomethacin (7 g) dissolved in ethyl alcohol (150 mL) is added, and the mixture is reacted at 50° C. for 20 mins. The precipitate is obtained through filtering under room temperature, which is re-crystallized from methanol over night and then filtrated to obtain KMUP-1-Indomethacin complex (13.2 g).

Provenance & Evidence