HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl chloroformate → Phenyl (1-phenyl-1H-pyrazol-5-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 1-Phenylpyrazol-5-ylamine | HCID 70006 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Phenyl (1-phenyl-1H-pyrazol-5-yl)carbamate | HCID 57925698 | — |
Reaction Steps
1-Phenyl-1H-pyrazol-5-amine (1 eq) was dissolved in DCE (0.1M), phenylchloroformate (1.1 eq) was added. The reaction was stirred 1 h, then diluted with DCM and washed with water and brine, dried and concentrated under reduced pressure to afford the product in quantitave yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470823B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-282fa14689f945139d04cf3c2dee1b2e |
| Source note | uspto-grants-2013_06 |