HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanesulfonyl chloride → (5RS,6RS)-8-Cyclopropanesulfonyl-6-hydroxy-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanesulfonyl chloride | HCID 2760919 | — |
| Reactant | HCID 58056623 | HCID 58056623 | — |
| Product | (5RS,6RS)-8-Cyclopropanesulfonyl-6-hydroxy-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 56602663 | — |
Reaction Steps
The title compound was prepared in analogy to example 2 step B from a mixture of (5SR,6RS)-6-hydroxy-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 2 step A) and cyclopropanesulfonyl chloride. Colourless solid. MS (ESI): 435.3 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470843B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-81d4093ba53c46a2aaddb679343afdeb |
| Source note | uspto-grants-2013_06 |