HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5SR,6RS)-8-Benzyl-6-hydroxy-2-[4-(2,2,2-trifluoro-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one → HCID 58056621, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5SR,6RS)-8-Benzyl-6-hydroxy-2-[4-(2,2,2-trifluoro-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one | HCID 58056622 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Product | HCID 58056621 | HCID 58056621 | — |
Reaction Steps
The title compound was prepared in analogy to example 2 step A from a mixture of (5SR,6RS)-8-benzyl-6-hydroxy-2-[4-(2,2,2-trifluoro-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one and Pearlman's catalyst under an atmosphere of hydrogen. White solid. MS (ESI): 329.2 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470843B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-00b04d589fbc4082b3e77976a9dd5668 |
| Source note | uspto-grants-2013_06 |