6-(2,4-difluorophenyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-one → 4-carboxy-6-(2,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one
Reaction equation
[F:1][c:2]1[cH:3][c:4](-[c:5]2[cH:6][c:7]([CH2:8][O:9][S:10]([CH3:11])(=[O:12])=[O:13])[c:14](=[O:15])[n:16]([CH2:17][CH:18]([CH3:19])[CH3:20])[n:21]2)[cH:22][cH:23][c:24]1[F:25].[F:26][c:27]1[c:28](-[c:34]2[cH:35][c:36]([C:45](=[O:46])[O:47][CH3:48])[c:37](=[O:44])[n:38]([CH2:40][CH:41]([CH3:42])[CH3:43])[n:39]2)[cH:29][cH:30][c:31]([F:33])[cH:32]1>>[F:26][c:27]1[c:28](-[c:34]2[cH:35][c:36]([C:45](=[O:46])[OH:47])[c:37](=[O:44])[n:38]([CH2:40][CH:41]([CH3:42])[CH3:43])[n:39]2)[cH:29][cH:30][c:31]([F:33])[cH:32]1Participants
3
Sources & evidence
- ORD record
- ord-68aae2ab53514290bebb93159d2feb19
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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