N-[3-(4-Hydroxyphenyl)propyl]acetamide → N-{3-[4-(5-Cyclopentyloxypyridin-2-yloxy)phenyl]propyl}acetamide

HRID 1260510Notes

Reaction equation

HRID 1260510 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][CH2:10][NH:11][C:12](=[O:14])[CH3:13])=[CH:4][CH:3]=1.Cl[C:16]1[CH:21]=[CH:20][C:19]([O:22][CH:23]2[CH2:27][CH2:26][CH2:25][CH2:24]2)=[CH:18][N:17]=1>>[CH:23]1([O:22][C:19]2[CH:20]=[CH:21][C:16]([O:1][C:2]3[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][CH2:10][NH:11][C:12](=[O:14])[CH3:13])=[CH:6][CH:7]=3)=[N:17][CH:18]=2)[CH2:24][CH2:25][CH2:26][CH2:27]1

Participants

3

Reactant 2

HCID 12238280N-[3-(4-Hydroxyphenyl)propyl]acetamideHCID 583690662-Chloro-5-cyclopentyloxypyridine

Product 1

HCID 44608621N-{3-[4-(5-Cyclopentyloxypyridin-2-yloxy)phenyl]propyl}acetamide

Procedure

N-[3-(4-Hydroxyphenyl)propyl]acetamide was reacted with 2-chloro-5-cyclopentyloxypyridine in analogy to example 2c. M+H+: 355.18.

Sources & evidence

ORD record
ord-e00ecc8ac4a947a7b89e8b49bb59a7b9
Source dataset
uspto-grants-2013_06
Patent number
US08470841B2

Reaction notes

Loading…