HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86656069, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-[3-(4-Hydroxyphenyl)-1-methylpropyl]acetamide | HCID 59956161 | — |
| Reactant | HCID 86656070 | HCID 86656070 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86656069 | HCID 86656069 | — |
Reaction Steps
2,3-Dichloro-5-isopropoxypyridine (514 mg, 2.496 mmol) and N-[3-(4-hydroxy-phenyl)-1-methylpropyl]acetamide (517 mg, 2.496 mmol) were reacted with sodium hydride in DMF in analogy to example 2c. Yield: 29 mg (3%), M+H+: 377.09. The isomer N-{3-[4-(2-chloro-5-isopropoxypyridin-3-yloxy)phenyl]-1-methylpropyl}acetamide was formed as further compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08470841B2 |
| Source dataset | uspto-grants-2013_06 |
| ORD ID | ord-e3c5df7584354a299df9e88364b10e33 |
| Source note | uspto-grants-2013_06 |