2-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine → HCID 67302294, compound

HRID 1260560Notes

Reaction equation

HRID 1260560 reaction equation
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][C:8](B2OC(C)(C)C(C)(C)O2)=[CH:7][N:6]=1)([CH3:3])[CH3:2].[OH:20][CH:21]1[CH2:26][CH2:25][CH:24]([CH2:27][CH2:28][CH:29]([NH:31][C:32](=[O:34])[CH3:33])[CH3:30])[CH2:23][CH2:22]1>>[CH:1]([O:4][C:5]1[N:6]=[CH:7][C:8]([O:20][CH:21]2[CH2:22][CH2:23][CH:24]([CH2:27][CH2:28][CH:29]([NH:31][C:32](=[O:34])[CH3:33])[CH3:30])[CH2:25][CH2:26]2)=[CH:9][CH:10]=1)([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 242087982-Isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridineHCID 49858095HCID 49858095, compound

Product 1

HCID 67302294HCID 67302294, compound

Procedure

2-Isopropoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine (913 mg, 3.47 mmol) and N-[3-(4-hydroxycyclohexyl)-1-methylpropyl]acetamide (740 mg, 3.47 mmol) were reacted in analogy to example 50a. Yield: 95 mg (8%), M+H+: 349.3.

Sources & evidence

ORD record
ord-364a222a2f694e5da7e3619ce9b3953d
Source dataset
uspto-grants-2013_06
Patent number
US08470841B2

Reaction notes

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