Acetic Anhydride → HCID 67071783, compound

HRID 1260566Notes

Reaction equation

F[C:2](F)(F)[C:3]([OH:5])=O.[CH:8]([O:11][C:12]1[N:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22](/[CH:25]=[CH:26]/[CH:27]([NH2:29])[CH3:28])=[CH:21][CH:20]=2)=[CH:14][CH:13]=1)([CH3:10])[CH3:9].C(OC(=O)C)(=O)C>>[CH:8]([O:11][C:12]1[N:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22](/[CH:25]=[CH:26]/[CH:27]([NH:29][C:3](=[O:5])[CH3:2])[CH3:28])=[CH:21][CH:20]=2)=[CH:14][CH:13]=1)([CH3:10])[CH3:9]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 67071666HCID 67071666, compound

Product 1

HCID 67071783HCID 67071783, compound

Procedure

(E)-3-[4-(6-Isopropoxy-pyridin-3-yloxy)-phenyl]-1-methyl-allylamine trifluoroacetate (63 mg, 0.154 mmol) was reacted with acetic anhydride in analogy to example 2a. M+H+: 341.2.

Sources & evidence

ORD record: ord-ff71c9a42f4e450d8152e8d49a539120
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470841B2

Reaction notes

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