Acetic Anhydride → HCID 58369095, compound

HRID 1260567Notes

Reaction equation

F[C:2](F)(F)[C:3]([OH:5])=O.[CH:8]([O:11][C:12]1[N:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22]([CH2:25][CH2:26][CH:27]([NH:29][CH3:30])[CH3:28])=[CH:21][CH:20]=2)=[CH:14][CH:13]=1)([CH3:10])[CH3:9].C(OC(=O)C)(=O)C>>[CH:8]([O:11][C:12]1[N:17]=[CH:16][C:15]([O:18][C:19]2[CH:24]=[CH:23][C:22]([CH2:25][CH2:26][CH:27]([N:29]([CH3:30])[C:3](=[O:5])[CH3:2])[CH3:28])=[CH:21][CH:20]=2)=[CH:14][CH:13]=1)([CH3:10])[CH3:9]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 67071711HCID 67071711, compound

Product 1

HCID 58369095HCID 58369095, compound

Procedure

{3-[4-(6-Isopropoxy-pyridin-3-yloxy)-phenyl]-1-methyl-propyl}-methyl-amine trifluoroacetate (27 mg, 0.086 mmol) was reacted with acetic anhydride in analogy to example 2a. M+H+: 357.2.

Sources & evidence

ORD record: ord-1d2dcb2fee1446969991740a0989d8e4
Source dataset: uspto-grants-2013_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08470841B2

Reaction notes

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