2-Methyl-4-nitrobenzonitrile → 4-Cyano-3-methylbenzenesulfonyl chloride

HRID 1260681Notes

Reaction equation

HRID 1260681 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:11])=[O:10])=[CH:5][C:4]=1OCC)#[N:2].[CH3:16]C1C=C([N+]([O-])=O)C=CC=1C#N>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([Cl:12])(=[O:10])=[O:11])=[CH:5][C:4]=1[CH3:16])#[N:2]

Participants

3

Reactant 2

HCID 43463672-Methyl-4-nitrobenzonitrileHCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 552801504-Cyano-3-methylbenzenesulfonyl chloride

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 2-methyl-4-nitro-benzonitrile.

Sources & evidence

ORD record
ord-a03d460ee85c48b08aff1a903d69dc14
Source dataset
uspto-grants-2013_06
Patent number
US08470848B2

Reaction notes

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