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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260690Generated: October 27, 2026

4-Amino-2-fluorobenzotrifluoride → 3-Fluoro-4-(trifluoromethyl)benzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1260690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Amino-2-fluorobenzotrifluorideHCID 2735914—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product3-Fluoro-4-(trifluoromethyl)benzene-1-sulfonyl chlorideHCID 86620153—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 3-fluoro-4-trifluoromethyl-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470848B2
Source datasetuspto-grants-2013_06
ORD IDord-1c343da11fa042d39114fe15fc3f7dba
Source noteuspto-grants-2013_06