Oxane-4-carboxylic acid → HCID 178523739, compound

Participants

Reaction Steps

The title compound, white solid (118 mg, 89%), MS (ISP) m/z=443.5 [(M+H)+], mp 236.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (132 mg, 0.3 mmol) and tetrahydropyran-4-yl-carboxylic acid.

Provenance & Evidence