Oxane-4-carboxylic acid → HCID 178523744, compound

Participants

Reaction Steps

The title compound, white solid (41 mg, 47%), MS (ISP) m/z=441.4 [(M+H)+], mp 211° C., was prepared in accordance with the general method of example 6 from 4-[2-(4-furo[2,3-c]pyridin-7-yl-piperazin-1-yl)-ethyl]-cyclohexylamine trihydrochloride (intermediate C) (88 mg, 0.2 mmol) and tetrahydropyran-4-yl-carboxylic acid.

Provenance & Evidence