3-[Bromo(4-cyanophenyl)methyl]benzonitrile → Ethyl 3-(1-{1-[(4-cyanophenyl)(3-cyanophenyl)methyl]azetidin-3-yl}-2-fluoro-2-methylpropyl)-5-fluorobenzoate
Reaction equation
[Br:22][CH:23]([c:24]1[cH:25][c:26]([C:27]#[N:28])[cH:29][cH:30][cH:31]1)[c:32]1[cH:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]1.[NH:1]1[CH2:2][CH:3]([CH:5]([C:6]([CH3:7])([CH3:8])[F:9])[c:10]2[cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][c:19]([F:21])[cH:20]2)[CH2:4]1>>[N:1]1([CH:23]([c:24]2[cH:25][c:26]([C:27]#[N:28])[cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][c:35]([C:38]#[N:39])[cH:36][cH:37]2)[CH2:2][CH:3]([CH:5]([C:6]([CH3:7])([CH3:8])[F:9])[c:10]2[cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][c:19]([F:21])[cH:20]2)[CH2:4]1Participants
3
Sources & evidence
- ORD record
- ord-fd403306a4f742b5878c9e7e3147ca04
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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