2-(1,4-Dioxan-2-yl)acetic acid → HCID 178520374, compound

Participants

Reaction Steps

The title compound, white solid (130 mg, 95%), MS (ISP) m/z=459.5 [(M+H)+], mp 194.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (132 mg, 0.3 mmol) and rac-(1,4-dioxan-2-yl)-acetic acid.

Provenance & Evidence