2-Methanesulfonylacetic acid → HCID 178504902, compound

Participants

Reaction Steps

The title compound, white solid (100 mg, 74%), MS (ISP) m/z=451.3 [(M+H)+], mp 187° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (132 mg, 0.3 mmol) and 2-methanesulfonyl-acetic acid.

Provenance & Evidence