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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260725Generated: November 2, 2026

Cyclobutanecarboxylic acid → HCID 178523720, compound

https://huagongshe.com/reaction/1260725

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanecarboxylic acidHCID 19494—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178523720HCID 178523720—

Reaction Steps

The title compound, white solid (48 mg, 73%), MS (ISP) m/z=413.4 [(M+H)+], mp 186° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) and cyclobutanecarboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-3adac06365ec462cb637915ba8d0b3a4
Source noteuspto-grants-2013_06