Ethanesulfonyl chloride → HCID 178477730, compound

Participants

Reaction Steps

The title compound, off-white solid (18 mg, 27%), MS (ISP) m/z=423.3 [(M+H)+], mp 190° C., was prepared in accordance with the general method of example 26 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) and ethanesulfonyl chloride.

Provenance & Evidence