2-(Oxolan-2-yl)acetic acid → HCID 178520302, compound

Participants

Reaction Steps

The title compound, white solid (45 mg, 64%), MS (ISP) m/z=443.5 [(M+H)+], mp 173.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) rac-(tetrahydro-furan-2-yl)-acetic acid.

Provenance & Evidence