Cyanoacetic acid → HCID 178511193, compound

Participants

Reaction Steps

The title compound, white solid (41 mg, 65%), MS (ISP) m/z=398.3 [(M+H)+], mp 215.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) 2-cyano-acetic acid.

Provenance & Evidence