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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260737Generated: November 1, 2026

Cyclopropanecarboxylic acid → HCID 178523718, compound

https://huagongshe.com/reaction/1260737

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxylic acidHCID 15655—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178523718HCID 178523718—

Reaction Steps

The title compound, white solid (31 mg, 49%), MS (ISP) m/z=399.3 [(M+H)+], mp 193° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (70.4 mg, 0.16 mmol) cyclopropane-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-4b1bd1a6aa2b4b75934994fb75631551
Source noteuspto-grants-2013_06