2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → HCID 178425866, compound

Participants

Reaction Steps

The title compound, white solid (110 mg, 97%), MS (ISP) m/z=454.4 [(M+H)+], mp 222.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 2-(3-methylisoxazol-5-yl)-acetic acid.

Provenance & Evidence