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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260745Generated: October 31, 2026

1-Hydroxy-1-cyclopropanecarboxylic acid → HCID 178523741, compound

https://huagongshe.com/reaction/1260745

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Hydroxy-1-cyclopropanecarboxylic acidHCID 2733160—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178523741HCID 178523741—

Reaction Steps

The title compound, white solid (14 mg, 14%), MS (ISP) m/z=415.4 [(M+H)+], mp 248.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 1-hydroxy-cyclopropane-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-d754add63e164a7b9924efc6db932e95
Source noteuspto-grants-2013_06