3-Hydroxyisovaleric acid → HCID 178459211, compound

Participants

Reaction Steps

The title compound, light yellow solid (57 mg, 53%), MS (ISP) m/z=431.5 [(M+H)+], mp 139° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 3-hydroxy-3-methyl-butanoic acid.

Provenance & Evidence