Methyl (S)-3-hydroxypentanoate → HCID 178456105, compound

Participants

Reaction Steps

The title compound, white solid (104 mg, 97%), MS (ISP) m/z=431.5 [(M+H)+], mp 217° C., was prepared in accordance with the general method of example 5 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and (S)-methyl 3-hydroxy-pentanoate.

Provenance & Evidence