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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1260768Generated: November 1, 2026

4-(4-Methylpiperazin-1-yl)benzoic acid → HCID 178480698, compound

https://huagongshe.com/reaction/1260768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4-Methylpiperazin-1-yl)benzoic acidHCID 736532—
ReactantHCID 178478590HCID 178478590—
ProductHCID 178480698HCID 178480698—

Reaction Steps

The title compound, white solid (116 mg, 87%), MS (ISP) m/z=533.4 [(M+H)+], mp 235.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 4-(4-methyl-piperazin-1-yl)-benzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08470828B2
Source datasetuspto-grants-2013_06
ORD IDord-c84f08cd1b9d4892818193092c149d46
Source noteuspto-grants-2013_06