4-Cyanobenzoic acid → HCID 178509884, compound

Participants

Reaction Steps

The title compound, off-white solid (111 mg, 97%), MS (ISP) m/z=460.5 [(M+H)+], mp 262.5° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 4-cyano-benzoic acid.

Provenance & Evidence