2-(1,2-Benzoxazol-3-yl)acetic acid → HCID 178520401, compound

Participants

Reaction Steps

The title compound, white solid (122 mg, 100%), MS (ISP) m/z=490.4 [(M+H)+], mp 211° C., was prepared in accordance with the general method of example 6 from trans-4-{2-[4-(2,3-dihydro-furo[2,3-c]pyridin-7-yl)-piperazin-1-yl]-ethyl}-cyclohexylamine trihydrochloride (intermediate B) (110 mg, 0.25 mmol) and 2-benzo[d]isoxazol-3-yl-acetic acid.

Provenance & Evidence